{"id":13504,"date":"2020-06-09T11:41:22","date_gmt":"2020-06-09T09:41:22","guid":{"rendered":"https:\/\/ggba.swiss\/breakthrough-in-veterinary-research-at-the-university-of-bern\/"},"modified":"2023-07-04T13:40:01","modified_gmt":"2023-07-04T11:40:01","slug":"breakthrough-in-veterinary-research-at-the-university-of-bern","status":"publish","type":"post","link":"https:\/\/ggba.swiss\/en\/breakthrough-in-veterinary-research-at-the-university-of-bern\/","title":{"rendered":"Breakthrough in veterinary research at the University of Bern"},"content":{"rendered":"<h4>A team of researchers from three faculties at the University of Bern have discovered how a bacterial infection in pigs can cause fatal intestinal bleeding, thus making a breakthrough in veterinary research. This discovery opens up promising prospects for vaccinations and medications for use in humans too.<\/h4>\n<p>New-born piglets often die painfully from infection with an intestinal bacterium. The <em>Clostridium perfringens<\/em> bacterium is part of the large Clostridium genus which can cause various fatal illnesses in animals and humans. These bacteria are dangerous because they produce extremely strong poisons (toxins) which cause targeted damage to the host\u2019s cells. Diseases such as botulism, tetanus, gas gangrene and intestinal infections, for example, are caused by Clostridium.<\/p>\n<p>10 years ago, a research group from the <a href=\"https:\/\/www.itpa.vetsuisse.unibe.ch\/index_eng.html\" target=\"_blank\" rel=\"noopener\">Institute of Animal Pathology<\/a> at the <a href=\"https:\/\/www.unibe.ch\/index_eng.html\" target=\"_blank\" rel=\"noopener\">University of Bern<\/a> demonstrated that the toxin produced by the bacteria kills vascular cells and thus causes bleeding in the piglet\u2019s intestine. Until now, however, it was unclear why the toxin attacked specifically these cells and not others. Today, Julia Bruggisser, biochemist and doctoral student at the Institute of Animal Pathology, has succeeded in solving the puzzle of this mechanism in an interdisciplinary collaboration between three faculties.<\/p>\n<h4><strong>Potential new forms of therapy for vascular diseases in humans<\/strong><\/h4>\n<p>A collaboration between multiple research groups at the University of Bern was essential for the success of the project. &#8220;For my research, I work in three laboratories at the University. Although it\u2019s challenging, I learn a lot and above all, it\u2019s fun,&#8221; says Julia Bruggisser.<\/p>\n<p>The discovery makes it possible to develop better vaccines in order to prevent the fatal disease in pigs. &#8220;We also want to investigate whether the attachment of beta toxins on the endothelial cells allows for the development of new forms of therapy, for vascular diseases in humans, for example. We have already started more collaborations within the University of Bern to this end,&#8221;\u00a0says Horst Posthaus, Professor at the <a href=\"https:\/\/www.dip.unibe.ch\/index_eng.html\" target=\"_blank\" rel=\"noopener\">Department of Infectious Diseases and Pathobiology<\/a> of the University of Bern.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers from three faculties at the University of Bern have discovered how a bacterial infection in pigs can cause fatal intestinal bleeding, thus making a breakthrough in veterinary research. This discovery opens up promising prospects for vaccinations and medications for use in humans too. New-born piglets often die painfully from infection with [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":13505,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[833],"tags":[939],"class_list":["post-13504","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-science","tag-veterinary"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Breakthrough in veterinary research at the University of Bern - Greater Geneva Bern area<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/staging.ggba.swiss\/en\/breakthrough-in-veterinary-research-at-the-university-of-bern\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Breakthrough in veterinary research at the University of Bern - Greater Geneva Bern area\" \/>\n<meta property=\"og:description\" content=\"A team of researchers from three faculties at the University of Bern have discovered how a bacterial infection in pigs can cause fatal intestinal bleeding, thus making a breakthrough in veterinary research. 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