{"id":13536,"date":"2020-06-22T11:46:11","date_gmt":"2020-06-22T09:46:11","guid":{"rendered":"https:\/\/ggba.swiss\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/"},"modified":"2023-07-04T13:40:02","modified_gmt":"2023-07-04T11:40:02","slug":"a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv","status":"publish","type":"post","link":"https:\/\/ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/","title":{"rendered":"A highly sensitive SARS-CoV-2 serological test developed at CHUV"},"content":{"rendered":"<h4>A team from Lausanne University Hospital has developed a new SARS-CoV-2 serological test in collaboration with the Swiss Federal Institute of Technology and the Swiss Vaccine Research Institute. This test is highly sensitive and can detect antibodies long after the subject has been infected.<\/h4>\n<p>The Immunology and Allergy Department team at Lausanne University Hospital (<a href=\"https:\/\/www.lausanneuniversityhospital.com\/home\" target=\"_blank\" rel=\"noopener\">CHUV<\/a>)\u00a0has developed a new, highly sensitive serological test using Luminex technology and the S protein in a trimeric conformation, very close to the one naturally found in coronaviruses. This high quality protein was produced by the team of the Laboratory of Virology and Genetics at <a href=\"https:\/\/www.epfl.ch\/en\/\" target=\"_blank\" rel=\"noopener\">EPFL<\/a>.<\/p>\n<p>The fast development of the new test was made possible by the use of very powerful technological platforms developed over many years by the <a href=\"https:\/\/swissvaccineresearchinstitute.ch\/\" target=\"_blank\" rel=\"noopener\">Swiss Vaccine Research Institute<\/a>.<\/p>\n<h4>A collaboration between several institutions for a significant advancement<\/h4>\n<p>The combined use of Luminex technology and the S protein significantly increases the sensitivity of this new serological test. An evaluation carried out by the Immunology and Allergy Department in collaboration with CHUV&#8217;s Microbiology Department shows that it is 15% to 30% more sensitive than four other commercial tests, three of which (Snibe, Epitope Diagnostics and Cobas) target the N protein and another (Liaison) the S protein.<\/p>\n<p>The new serological test developed by CHUV allows the detection of SARS-CoV-2 antibodies longer after an infection, even in paucisymptomatic (with few symptoms) and asymptomatic (without symptoms) people. This is an important advancement for future population studies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team from Lausanne University Hospital has developed a new SARS-CoV-2 serological test in collaboration with the Swiss Federal Institute of Technology and the Swiss Vaccine Research Institute. This test is highly sensitive and can detect antibodies long after the subject has been infected. The Immunology and Allergy Department team at Lausanne University Hospital (CHUV)\u00a0has [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":13537,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[833],"tags":[884],"class_list":["post-13536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-science","tag-covid-19"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A highly sensitive SARS-CoV-2 serological test developed at CHUV - Greater Geneva Bern area<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A highly sensitive SARS-CoV-2 serological test developed at CHUV - Greater Geneva Bern area\" \/>\n<meta property=\"og:description\" content=\"A team from Lausanne University Hospital has developed a new SARS-CoV-2 serological test in collaboration with the Swiss Federal Institute of Technology and the Swiss Vaccine Research Institute. This test is highly sensitive and can detect antibodies long after the subject has been infected. The Immunology and Allergy Department team at Lausanne University Hospital (CHUV)\u00a0has [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/\" \/>\n<meta property=\"og:site_name\" content=\"Greater Geneva Bern area\" \/>\n<meta property=\"article:published_time\" content=\"2020-06-22T09:46:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-07-04T11:40:02+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/staging.ggba.swiss\/app\/uploads\/2023\/06\/Covid-Test-3.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"945\" \/>\n\t<meta property=\"og:image:height\" content=\"429\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"mathieu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"mathieu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/\"},\"author\":{\"name\":\"mathieu\",\"@id\":\"https:\/\/staging.ggba.swiss\/en\/#\/schema\/person\/de091cdfd7d8bce46f9b8b1cf9d868ab\"},\"headline\":\"A highly sensitive SARS-CoV-2 serological test developed at CHUV\",\"datePublished\":\"2020-06-22T09:46:11+00:00\",\"dateModified\":\"2023-07-04T11:40:02+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/\"},\"wordCount\":250,\"image\":{\"@id\":\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ggba.swiss\/app\/uploads\/2023\/06\/Covid-Test-3.jpg\",\"keywords\":[\"Covid-19\"],\"articleSection\":[\"Life sciences\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/\",\"url\":\"https:\/\/staging.ggba.swiss\/en\/a-highly-sensitive-sars-cov-2-serological-test-developed-at-chuv\/\",\"name\":\"A highly sensitive SARS-CoV-2 serological test developed at CHUV - 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