{"id":22796,"date":"2024-02-26T10:23:36","date_gmt":"2024-02-26T09:23:36","guid":{"rendered":"https:\/\/ggba.swiss\/?p=22796"},"modified":"2024-02-26T10:23:37","modified_gmt":"2024-02-26T09:23:37","slug":"csem-and-clexbio-unveil-groundbreaking-bioreactor-to-advance-cardiovascular-treatment","status":"publish","type":"post","link":"https:\/\/ggba.swiss\/en\/csem-and-clexbio-unveil-groundbreaking-bioreactor-to-advance-cardiovascular-treatment\/","title":{"rendered":"CSEM and ClexBio unveil groundbreaking bioreactor to advance cardiovascular treatment"},"content":{"rendered":"\n<p>The collaboration between <a href=\"https:\/\/www.csem.ch\/en\/\">CSEM<\/a> and <a href=\"https:\/\/www.clexbio.com\/\">ClexBio<\/a> has yielded a prototype bioreactor designed for the production of functional vein implants from stem-cell-derived human tissue. These implants are intended to seamlessly integrate into the patient&#8217;s body, transforming into living tissue over time.<\/p>\n\n\n\n<p>Leveraging ClexBio\u2019s expertise in regenerative medicine and hydrogels, alongside CSEM\u2019s prowess in automation and micro physiological systems, the partnership has brought to life a biodegradable matrix capable of creating human tissue.<\/p>\n\n\n\n<p>ClexBio introduces its platform technology, VivoSet, a cell-biomaterial formulation that engineers tissues with complex architectures, including veins. This technology, combined with CSEM\u2019s innovative approach to bioreactor design, replicates the natural tubular structure of veins, fostering the production of tissue-engineered vein grafts. These grafts are designed to be implanted &#8220;off the shelf,&#8221; offering a regenerative solution devoid of immune response, thus heralding a potential breakthrough in modern medicine.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Incredible potential for novel cell therapies<\/h4>\n\n\n\n<p>The project, dubbed Supervene, aims to automate the fabrication process for regenerative medicine, transitioning from laboratory to clinical application. \u201cVivoSet is a new technology that can unlock the incredible potential of novel cell therapies,\u201d said St\u00e9phanie Boder-Pasche, Senior Project Manager at CSEM. This sentiment was echoed by Gilles Weder, Head of Research &amp; BD at CSEM, who underscored the necessity of a closed, automated bio-manufacturing system for producing such implants.<\/p>\n\n\n\n<p>With the system now developed, ClexBio will undertake further pre-clinical testing in larger animal models, with the ultimate goal of conducting in-human studies. CEO &amp; Co-Founder of ClexBio, Armend H\u00e5ti, highlighted the significance of this development: \u201cWe are truly excited about the paradigm shift this may usher in for human surgery and the treatment of damaged tissues.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CSEM and ClexBio, a Nordic startup specializing in regenerative medicine, have developed a novel bioreactor capable of cultivating human veins in the laboratory.<\/p>\n","protected":false},"author":6,"featured_media":22797,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[833],"tags":[943,907,926,902,886],"class_list":["post-22796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-science","tag-advanced-manufacturing","tag-engineering","tag-medtech","tag-personalized-medicine","tag-rd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CSEM and ClexBio unveil groundbreaking bioreactor | GGBa<\/title>\n<meta name=\"description\" content=\"Neuch\u00e2tel&#039;s CSEM and ClexBio have developed a novel bioreactor capable of cultivating human veins in the laboratory.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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