{"id":39114,"date":"2026-06-03T09:05:43","date_gmt":"2026-06-03T07:05:43","guid":{"rendered":"https:\/\/ggba.swiss\/?p=39114"},"modified":"2026-06-03T09:12:49","modified_gmt":"2026-06-03T07:12:49","slug":"csem-helps-bring-real-time-glucose-monitoring-to-bioreactor-manufacturing","status":"publish","type":"post","link":"https:\/\/ggba.swiss\/en\/csem-helps-bring-real-time-glucose-monitoring-to-bioreactor-manufacturing\/","title":{"rendered":"CSEM helps bring real-time glucose monitoring to bioreactor manufacturing"},"content":{"rendered":"\n<p><a href=\"https:\/\/www.csem.ch\/en\/\">CSEM<\/a>, the Neuch\u00e2tel-based research and technology organization, contributed critical engineering expertise to the development of GlucoSense, a sensor by <a href=\"https:\/\/www.hamiltoncompany.com\/\">Hamilton Bonaduz AG<\/a> that enables continuous, real-time glucose monitoring directly inside bioreactors. The collaboration addressed one of the longstanding technical gaps in biologics manufacturing, where glucose levels have traditionally been measured through delayed offline sampling.<\/p>\n\n\n\n<p>Glucose is a key energy source for the living cells grown inside bioreactors to produce biologic medicines such as antibody therapies. Fluctuations or drops in glucose concentration can affect cell productivity and product consistency. GlucoSense uses infrared light to track glucose levels continuously within the culture medium, giving operators immediate visibility into process conditions.<\/p>\n\n\n\n<p>CSEM&#8217;s role focused on the hermetic integration of the sensing element, membrane bonding and material selection, which are engineering challenges essential to ensuring the sensor&#8217;s long-term stability and reliability in demanding bioprocess environments. Performance testing showed the system delivered stable monitoring throughout cultivation runs following a single initial calibration, and a study conducted at the University of Applied Sciences and Arts Northwestern Switzerland (<a href=\"https:\/\/www.fhnw.ch\/en\/\">FHNW<\/a>) confirmed reliable operation over runs lasting several weeks.<\/p>\n\n\n\n<p>For a broader perspective on CSEM\u2019s role in Switzerland\u2019s innovation ecosystem, listen to our&nbsp;<a href=\"https:\/\/open.spotify.com\/show\/3oEHA4iaJSBZ5Qu7saxrqC\">Getting Serious podcast conversation with Dr. Alexandre Pauchard<\/a>, CEO of CSEM, in which he explores what keeps Switzerland at the top of global innovation rankings.<\/p>\n\n\n\n<figure class=\"wp-block-embed aligncenter is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Switzerland Is #1 in Innovation, But for How Long? (A Conversation with Alexandre Pauchard)\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/q4OSD2cBcoU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Neuch\u00e2tel\u2019s CSEM contributed system integration and bonding expertise to the development of Hamilton&#8217;s GlucoSense, a sensor that delivers continuous glucose monitoring inside bioreactors used in biologics production.<\/p>\n","protected":false},"author":6,"featured_media":39115,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[833],"tags":[943,912,963,926,901],"class_list":["post-39114","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-science","tag-advanced-manufacturing","tag-biotech","tag-medical-devices","tag-medtech","tag-technology-park"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CSEM helps bring glucose monitoring to bioreactor manufacturing<\/title>\n<meta name=\"description\" content=\"Neuch\u00e2tel\u2019s CSEM contributed system integration and bonding expertise to the development of Hamilton&#039;s GlucoSense.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ggba.swiss\/en\/csem-helps-bring-real-time-glucose-monitoring-to-bioreactor-manufacturing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CSEM helps bring glucose monitoring to bioreactor manufacturing\" \/>\n<meta property=\"og:description\" content=\"Neuch\u00e2tel\u2019s CSEM contributed system integration and bonding expertise to the development of Hamilton&#039;s GlucoSense.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ggba.swiss\/en\/csem-helps-bring-real-time-glucose-monitoring-to-bioreactor-manufacturing\/\" \/>\n<meta property=\"og:site_name\" content=\"Greater Geneva Bern area\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-03T07:05:43+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-06-03T07:12:49+00:00\" 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