{"id":40205,"date":"2026-11-02T11:00:00","date_gmt":"2026-11-02T10:00:00","guid":{"rendered":"https:\/\/ggba.swiss\/?p=40205"},"modified":"2026-11-02T09:28:35","modified_gmt":"2026-11-02T08:28:35","slug":"lepfl-publie-un-atlas-tissulaire-libre-pour-aider-lia-a-comprendre-le-cancer","status":"publish","type":"post","link":"https:\/\/ggba.swiss\/fr\/lepfl-publie-un-atlas-tissulaire-libre-pour-aider-lia-a-comprendre-le-cancer\/","title":{"rendered":"L&rsquo;EPFL publie un atlas tissulaire libre pour aider l&rsquo;IA \u00e0 comprendre le cancer"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Des chercheurs de l&rsquo;<a href=\"https:\/\/www.epfl.ch\/fr\/\">EPFL<\/a> ont publi\u00e9 <a href=\"https:\/\/spora.bioimagearchive.org\/projects\/spora\">spora<\/a>, un atlas de r\u00e9f\u00e9rence d&rsquo;images de prot\u00e9omique spatiale et de donn\u00e9es m\u00e9dicales, avec l&rsquo;Institut europ\u00e9en de bio-informatique (<a href=\"https:\/\/www.ebi.ac.uk\/\">EMBL-EBI<\/a>), qui l&rsquo;h\u00e9berge dans sa BioImage Archive. La prot\u00e9omique spatiale mesure des dizaines de prot\u00e9ines tout en pr\u00e9servant leur position dans le tissu, ce qui montre comment les cellules sont organis\u00e9es et interagissent. L&rsquo;EPFL pr\u00e9sente spora comme la plus grande collection librement accessible de telles images et donn\u00e9es au monde.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">L&rsquo;atlas r\u00e9unit 13&rsquo;546 images multiplex de 5&rsquo;477 patients, couvrant 14 origines de tissus et cinq technologies d&rsquo;imagerie, avec des images d&rsquo;histopathologie appari\u00e9es lorsqu&rsquo;elles sont disponibles. L&rsquo;\u00e9quipe a consacr\u00e9 deux ans \u00e0 organiser les images, \u00e0 standardiser les annotations de prot\u00e9ines, \u00e0 relier les informations m\u00e9dicales et \u00e0 identifier les cellules individuelles, afin de faciliter la combinaison de jeux de donn\u00e9es issus de laboratoires diff\u00e9rents, qui utilisent souvent des \u00e9quipements, des prot\u00e9ines et des formats de stockage diff\u00e9rents.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Des outils pour la recherche en IA<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">spora comprend trois composants : spora[data], qui regroupe images et annotations dans un format commun, spora[io], une biblioth\u00e8que Python pour charger des r\u00e9gions de tissus, combiner des cohortes et pr\u00e9parer des donn\u00e9es d&rsquo;entra\u00eenement, et spora[bench], une suite de tests de performance avec des t\u00e2ches comme l&rsquo;identification de cellules, la classification de types cellulaires et la pr\u00e9diction de variables cliniques. Les chercheurs peuvent s&rsquo;en servir pour v\u00e9rifier si des r\u00e9sultats se confirment d&rsquo;une \u00e9tude \u00e0 l&rsquo;autre, si des mod\u00e8les reconnaissent les types de cellules avec diff\u00e9rents panels de prot\u00e9ines et si un mod\u00e8le entra\u00een\u00e9 dans un h\u00f4pital fonctionne sur des images d&rsquo;un autre. Les mod\u00e8les d&rsquo;IA associ\u00e9s ont \u00e9t\u00e9 entra\u00een\u00e9s sur des capacit\u00e9s de calcul \u00e0 grande \u00e9chelle via la <a href=\"https:\/\/www.swiss-ai.org\/\">Swiss AI Initiative<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Le projet a \u00e9t\u00e9 dirig\u00e9 par Charlotte Bunne, qui dirige le groupe Artificial Intelligence in Molecular Medicine (AIMM) \u00e0 l&rsquo;EPFL, avec l&rsquo;H\u00f4pital universitaire de Zurich, l&rsquo;Universit\u00e9 de Zurich, les <a href=\"https:\/\/www.hug.ch\/\">H\u00f4pitaux universitaires de Gen\u00e8ve<\/a> (HUG) et l&rsquo;<a href=\"https:\/\/www.unige.ch\/\">Universit\u00e9 de Gen\u00e8ve<\/a>, et a \u00e9t\u00e9 d\u00e9velopp\u00e9 dans le cadre de la National AI Initiative for Precision Oncology. \u00ab Notre objectif est de transformer ce que nous apprenons de milliers d&rsquo;\u00e9chantillons de tissus en connaissances qui peuvent aider chaque patient \u00bb, d\u00e9clare Charlotte Bunne. L&rsquo;\u00e9quipe pr\u00e9voit d&rsquo;ajouter davantage de tissus, de maladies et de technologies d&rsquo;imagerie.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>R\u00e9alis\u00e9 avec des partenaires \u00e0 Zurich et \u00e0 Gen\u00e8ve, spora est un atlas de prot\u00e9omique spatiale que l&rsquo;EPFL d\u00e9crit comme la plus grande collection librement accessible de ce type au monde, destin\u00e9 \u00e0 acc\u00e9l\u00e9rer la recherche en IA sur le d\u00e9veloppement des maladies.<\/p>\n","protected":false},"author":6,"featured_media":40202,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[843],"tags":[1179,1180,1188,1142],"class_list":["post-40205","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sciences-de-la-vie","tag-artificial-intelligence-fr-2","tag-digital-health-fr-2","tag-healthcare-fr-2","tag-rd-fr-2"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L&#039;EPFL lance spora, un atlas tissulaire ouvert pour l&#039;IA | GGBa<\/title>\n<meta name=\"description\" content=\"R\u00e9alis\u00e9 avec des partenaires \u00e0 Gen\u00e8ve, spora r\u00e9unit 13&#039;546 images de 5&#039;477 patients pour acc\u00e9l\u00e9rer la recherche en IA sur le 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